Product Details
Formula Automated Rapid AST System (Single-Cell Counting Method)
Rapid AST System, which can obtain microbial susceptibility results within 2 hours, is a major breakthrough in microbiological testing and is of revolutionary significance in this field.
Product Details
Formula Automated Rapid AST System (Single-Cell Counting Method)
Product Overview
The Automated Rapid AST System of Scenker Biological Technology Co., Ltd, applies the Kurt Principle in the field of microbial AST, different from the traditional turbidimetry AST, which is a pioneering technology all over the world. Observing the inhibition of antibiotics on microorganisms from a microscopic point of view, rapid AST technology can obtain the result within 2 hours, which is much faster than traditional AST that taking 18-24 hours. It is a major breakthrough in microbiological testing and is of revolutionary significance in this field.
Product Features
Innovative: In principle, the inhibitory effect of antibiotics on microorganisms is analyzed from the microscopic level for the detection of individual cell counts, which is different from the existing optical turbidity analysis methods detected from the macroscopic population perspective.
Fast: 2hr to get a precise MIC, different from the existing products 8-24 hours to get MIC, can be perfectly matched with the current mass spectrometer.
Accurate: In Peking Union Medical College Hospital, the standard strain quality control range and the clinical intestinal strain were verified by MIC matching with the reference method, and it had good performance performance.
Automatic: Automatic incubation, detection and reporting in the machine, the operation process is automatic and simple.
Application Prospects
Formula Automated Rapid AST System (Single-Cell Counting Method) is based on the micro-broth dilution method, follows the current commonly used drug susceptibility interpretation standards EUCAST and CLSI standards, and has high compatibility with clinical use habits; combined with MALDI-TOF MS can achieve rapid identification and Antibiotic Susceptibility Test report within 2 hours, which has better application prospects in the detection of drug susceptibility in blood samples and urine samples.
Rapid AST System Improves Medication in Patients with Simple Urinary Tract Infection
Diagnosis and management of urinary tract infections usually take 48 hours to obtain the results of an antibiotic susceptibility test (AST). Due to the untimely test results, empirical medication is mostly used in clinical treatment. The use of broad-spectrum antibiotics increases the risk of new infections; if ineffective antibiotics are chosen, they can worsen infections, cause suffering for patients, and increase medical costs. Therefore, shortening the time of AST results is an important factor in improving the effectiveness of diagnosis and treatment, especially urinary tract infections caused by multidrug-resistant bacteria.
For most patients with simple urinary tract infection, the direct urine culture time is 18 hours, while the Formula Automated Rapid AST System (Single-Cell Counting Method) can obtain accurate susceptibility test results within 2 hours, so that urine susceptibility reports can be issued within 20 hours. Faster and accurate UTI ID/AST helps clinicians to allow patients to receive the right targeted therapy more quickly, improving prognosis and antimicrobial sensitivity.
Application of Rapid AST System (Single-Cell Counting Method) in Blood Culture-positive Specimens
Studies have shown that in patients with bloodstream infection, after the onset of shock, the survival rate of patients decreased by 7.6% for every 1 hour delay in the use of effective antibiotics, and the mortality rate increased significantly.
For severe bloodstream infections, the timeliness of antibiotic test results is measured in minutes, and it is particularly important to obtain susceptibility reports as soon as possible, and switch from empiric to precision treatment. According to statistics, nearly 80% of the positive results of blood culture appear within 24 hours, if use conventional drug susceptibility, it is necessary to scribble the seed, the average growth time is 18 hours, and then 8-24 hours to get results, the overall time is 50-66 hours; while Rapid AST System (Single-Cell Counting Method) can detect susceptibility directly or routinely after culture, and the susceptibility test time is only 2 hours, and the overall time is shortened to 26-44 hours.
For Enterobacteria, which account for up to 52% of the blood culture, the average positive time is only 16 hours, and Rapid AST System (Single-Cell Counting Method) can be used to conduct rapid AST of Enterobacteria such as lung grams and large intestine in the intensive care department, so that the TAT time is reduced to 18-36 hours, which is conducive to the early transformation from empirical medication to precision medication and improve the accuracy of antibiotic use.
Formula Automated Rapid AST System (Single-Cell Counting Method) and supporting reagents has been strongly supported by domestic and foreign experts. Its appearance can effectively improve the level of diagnosis and treatment of infectious diseases, and contribute to the rational use of antibiotics, strengthen antibiotic control, and curb antibiotic resistance.
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